Description
Buy BPC-157 Peptide Online EU
Welcome to euresearchpeptides.com — your trusted source for premium, laboratory-grade research peptides in Europe. Our BPC-157 peptide (Body Protection Compound-157) is a synthetic pentadecapeptide widely studied for its remarkable cytoprotective, angiogenic, and regenerative properties in preclinical research models. buy BPC-157 peptide Europe
What Is BPC-157 Peptide?
BPC-157, also known as PL 14736 or stable gastric pentadecapeptide, is a synthetic peptide consisting of 15 amino acids. It is derived from a naturally occurring protective compound found in human gastric juice and has been the subject of extensive preclinical research since the 1990s. Unlike full-length proteins, this pentadecapeptide exhibits remarkable stability and resistance to proteolytic degradation, making it a valuable research tool for studying tissue repair, inflammation modulation, and cytoprotection. buy BPC-157 peptide Europe
This peptide is strictly intended for laboratory research use only and is not for human consumption. Our BPC-157 is manufactured using solid-phase peptide synthesis (SPPS) and purified via high-performance liquid chromatography (HPLC) to achieve purity exceeding 99%.
How BPC-157 Works: Mechanism of Action
BPC-157 exerts its biological effects through several well-characterized pathways, primarily centered on angiogenesis and nitric oxide modulation .
Angiogenesis and VEGFR2 Activation: Research demonstrates that BPC-157 activates the VEGFR2 pathway and promotes angiogenesis through the Akt-eNOS axis. This stimulation of new blood vessel formation is crucial for tissue healing and regeneration, particularly in poorly vascularized tissues such as tendons and ligaments. buy BPC-157 peptide Europe
Nitric Oxide System Modulation: Unlike agents that simply increase or decrease NO, BPC-157 exhibits a distinctive effect on the NO-system, always combined with counteraction of free radical formation. It can both increase and decrease NO levels as needed, maintaining the body’s protective functions while preventing cytotoxic damage.
Growth Factor Signaling: BPC-157 enhances growth hormone receptor expression and modulates ERK1/2 signaling pathways involved in cell growth, fibroblast activity, and tissue repair.
Inflammatory Cytokine Suppression: The peptide reduces pro-inflammatory cytokines including TNF-alpha and IL-6, contributing to its anti-inflammatory effects in various research models.
Research Applications
BPC-157 peptide has been investigated across multiple research domains :
| Research Area | Application |
|---|---|
| Gastrointestinal Research | Studies on inflammatory bowel disease, gastric ulcers, NSAID-induced injury, intestinal anastomosis healing, and leaky gut syndrome |
| Musculoskeletal Research | Investigations into tendon healing, ligament repair, muscle regeneration, and bone healing |
| Neuroprotection Research | Studies on traumatic brain injury, spinal cord injury, peripheral nerve damage, and neuroinflammation |
| Cardiovascular Research | Research on hypertension, vascular integrity, and ischemia-reperfusion injury |
| Wound Healing Studies | Preclinical models of skin wound healing, corneal repair, and soft tissue regeneration
|
Product Specifications
| Attribute | Specification |
|---|---|
| Peptide Name | BPC-157 (Body Protection Compound-157) |
| Sequence | H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH |
| Molecular Formula | C62H98N16O22 |
| Molecular Weight | 1419.55 – 1419.57 Da |
| CAS Number | 137525-51-0 |
| Purity | >99% (HPLC verified, MS confirmed) |
| Appearance | White to off-white lyophilized powder |
| Endotoxin Level | <0.05 EU/mg |
| Salt Form | Acetate / TFA (specify upon order) |
Solubility Profile
BPC-157 exhibits excellent solubility in aqueous solutions:
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Primary solvent: Sterile distilled water or bacteriostatic water
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Concentration guideline: Reconstitute at not less than 100 µg/mL
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Alternative solvents: Sterile saline or dilute acetic acid
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Solubility: Freely soluble in water
Reconstitution Guideline for Research:
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For a 5 mg vial: Add 1 mL of bacteriostatic water for 5 mg/mL concentration
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For a 10 mg vial: Add 2 mL of bacteriostatic water for 5 mg/mL concentration
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For a 15 mg vial: Add 3 mL of bacteriostatic water for 5 mg/mL concentration
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For a 20 mg vial: Add 4 mL of bacteriostatic water for 5 mg/mL concentration
Gently swirl or roll the vial until fully dissolved. Do not shake vigorously as this may denature the peptide.
Stability and Storage Recommendations
| Condition | Storage Method |
|---|---|
| Lyophilized Powder | Store at -20°C or below, desiccated, protected from light and moisture |
| Reconstituted Solution | Refrigerate at 2-8°C, use within 7 days |
| Long-term Storage | Keep lyophilized and frozen; for longer storage, add carrier protein (0.1% HSA or BSA) and store at -20°C or below |
| Shelf Life | 24 months when stored properly in lyophilized form |
| Important | Avoid repeated freeze-thaw cycles |
RT Stability Note: Lyophilized BPC-157 is stable at room temperature for up to 3 weeks, but long-term storage requires freezing conditions .
Quality Standards at EU Research Peptides
Our BPC-157 peptide is manufactured under strict quality control protocols:
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Synthesis: Solid-phase peptide synthesis (SPPS) with Fmoc chemistry
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Purification: HPLC purification to >99% purity
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Verification: Mass spectrometry (MS) confirmation of molecular weight
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Quality Control: Each batch includes Certificate of Analysis (COA) with HPLC chromatogram and MS spectrum
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Facility: ISO-classified cleanroom manufacturing
Known Preclinical Research Findings
The scientific literature on BPC-157 spans over three decades. Key findings from peer-reviewed studies include :
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Gastrointestinal Protection: Preclinical studies demonstrate BPC-157’s ability to heal various GI ulcers, protect against NSAID-induced injury, and improve outcomes in inflammatory bowel disease models
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Tendon and Ligament Healing: Research in animal models shows accelerated healing of transected tendons and improved functional recovery
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Neuroprotective Effects: Studies indicate BPC-157 counteracts neurodegenerative disturbances in Parkinson’s disease and Alzheimer’s disease models
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Anti-inflammatory Activity: The peptide reduces pro-inflammatory cytokines and oxidative stress markers
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Angiogenic Properties: BPC-157 promotes controlled angiogenesis without the tumorigenic risks associated with other growth factors
Important Research Note: While over 500 preclinical studies exist, large-scale human clinical trials remain limited. BPC-157 is considered an investigational research compound and should be handled accordingly .
Handling Protocols
For research use only. Proper handling ensures experimental integrity:
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Allow vials to reach room temperature before opening to minimize condensation
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Reconstitute by injecting diluent slowly down the vial wall; avoid foaming
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Gently swirl or roll until fully dissolved — do not shake
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Label with date, concentration, and lot number
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Store reconstituted peptide at 2-8°C and use within 7 days
Why Researchers Choose EU Research Peptides
European-Based Operations: We are strategically located in the EU, ensuring fast, reliable shipping across Europe without customs delays. Our peptides are available for researchers in Germany, France, the Netherlands, Spain, Italy, and all EU member states.
Premium Quality: Every peptide batch undergoes rigorous third-party testing for purity, stability, and endotoxin levels. Our BPC-157 exceeds 99% purity as determined by RP-HPLC analysis .
Research Compliance: All products are labeled “For Research Use Only” and comply with EU chemical regulations. Each order includes full documentation including COA, MSDS, and reconstitution protocols.
Technical Support: Our team provides comprehensive documentation and technical guidance for research applications.
Competitive Pricing: Volume discounts available for research institutions and bulk orders.
👉 Explore our complete catalog of research peptides at our official homepage.
Safety Considerations
BPC-157 peptide is intended for laboratory research purposes only. It is not for human consumption, therapeutic use, or veterinary applications. This compound is not approved by the European Medicines Agency (EMA) for clinical use and is classified as an investigational research chemical . Researchers should:
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Follow institutional biosafety guidelines
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Use appropriate personal protective equipment (PPE)
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Handle all peptides with sterile technique
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Dispose of materials according to local regulations
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Note that BPC-157 is prohibited by WADA for use in competitive sports
Frequently Asked Questions (FAQ)
What is BPC-157 peptide?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids . It is derived from a protective compound naturally found in human gastric juice and has been extensively studied in preclinical research for its cytoprotective, anti-inflammatory, and regenerative properties.
What is the molecular formula and weight of BPC-157?
The molecular formula is C62H98N16O22 with a molecular weight of approximately 1419.55 – 1419.57 Daltons.
What is the amino acid sequence of BPC-157?
The sequence is H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH .
What purity level does EU Research Peptides offer for BPC-157?
Our BPC-157 peptide is tested at >99% purity by HPLC with mass spectrometry confirmation . Each batch includes a Certificate of Analysis (COA) with detailed purity data.
How should I store BPC-157 peptide?
Lyophilized BPC-157 should be stored at -20°C or below, desiccated, and protected from light and moisture . After reconstitution, refrigerate at 2-8°C and use within 7 days . Avoid repeated freeze-thaw cycles. For long-term storage, consider adding a carrier protein such as 0.1% HSA or BSA .
Is BPC-157 peptide soluble in water?
Yes, BPC-157 is freely soluble in water . It is recommended to reconstitute lyophilized BPC-157 in sterile 18MΩ-cm H2O at not less than 100 µg/mL, which can then be further diluted with other aqueous solutions .
What is the CAS number for BPC-157?
The CAS number is 137525-51-0 .
What are the primary research applications for BPC-157?
BPC-157 is studied in gastrointestinal research (IBD, gastric ulcers, NSAID-induced injury), musculoskeletal research (tendon, ligament, and muscle healing), neuroprotection (traumatic brain injury, spinal cord injury, neurodegenerative disease models), and wound healing studies .
What is the mechanism of action of BPC-157?
BPC-157 activates VEGFR2 and promotes angiogenesis via the Akt-eNOS axis, modulates the nitric oxide system, enhances growth factor signaling, and reduces pro-inflammatory cytokines .
Is BPC-157 approved for clinical use?
No. BPC-157 is not approved by the European Medicines Agency (EMA) or FDA for clinical use. It is classified as an investigational research chemical and is intended for laboratory research purposes only .
Is BPC-157 legal for research in Europe?
BPC-157 can be imported and sold for research purposes with appropriate labeling (“for research use only”). It is not approved as a pharmaceutical product and cannot be prescribed or sold for human consumption in the EU .
Is BPC-157 banned in sports?
Yes. The World Anti-Doping Agency (WADA) banned BPC-157 in 2022, classifying it as an S0 substance (substance with no approved medical use) .
Can I purchase BPC-157 peptide in bulk?
Yes, EU Research Peptides offers volume discounts for bulk orders. Contact our customer service team for customized quotes.
What documentation is provided with each order?
Each order includes a Certificate of Analysis (COA) with HPLC chromatogram and MS spectrum, material safety data sheet (MSDS), and reconstitution protocol.
How long does shipping take within Europe?
Standard shipping within the EU takes 3-5 business days. Express shipping options are available for urgent research needs.
What is the endotoxin level in your BPC-157 product?
Our BPC-157 peptide has endotoxin levels below 0.05 EU/mg, verified by third-party testing.
Is BPC-157 stable at room temperature?
Lyophilized BPC-157 is stable at room temperature for up to 3 weeks. For long-term storage, freezing at -20°C or below is required .
What is the half-life of BPC-157 in research models?
Preclinical studies indicate BPC-157 has a half-life of less than 30 minutes and is metabolized in the liver with renal clearance .
Has BPC-157 been studied in humans?
To date, only three small pilot human studies have been published, including studies on knee pain (16 patients), interstitial cystitis (12 patients), and intravenous safety (2 participants). Large-scale, placebo-controlled clinical trials are needed to establish efficacy and safety .
What is the difference between BPC-157 acetate and BPC-157 TFA?
Both are salt forms of the same peptide. Acetate salt is often preferred for research requiring lower cytotoxicity, while TFA salt is common in standard peptide synthesis. Both are suitable for most in vitro and in vivo research applications.
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