HGH

35.00

 

 

Technical Specifications

Parameter Specification
Product Name Recombinant Human Growth Hormone (HGH / Somatotropin)
Amino Acid Count 191 amino acids
Molecular Weight ~22 kDa (approximately 22,000 Daltons)
Molecular Formula C₉₉₀H₁₅₂₈N₂₆₂O₃₀₀S₇
Sequence Phe27-Pro216 (mature protein)
Purity >98% by SDS-PAGE and HPLC
Biological Activity ED50 < 0.1 ng/mL in Nb2-11 lymphoma cell proliferation assay
Endotoxin Level <0.1 ng/µg (1 EU/µg)
Expression System E. coli (tag-free)
Accession Number P01241 (UniProt)
Gene ID 2688
Physical Form Sterile lyophilized powder
Appearance White to off-white cake

 

Category: Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Description

Buy research grade human growth hormone (HGH) Peptides EU

Human Growth Hormone (HGH), also known as somatotropin, is a 191-amino acid single-chain polypeptide that serves as a cornerstone reagent for endocrinology research, cell biology studies, and metabolic pathway investigation. This research-grade recombinant HGH is produced in E. coli expression systems and purified to exceptional standards, making it suitable for a wide range of laboratory applications including receptor binding assays, cell proliferation studies, and signaling pathway analysis. Buy research grade human growth hormone (HGH) Online EU

For researchers seeking buy peptides EU solutions with documented purity and stability profiles, this HGH product represents a reliable choice for experimental workflows requiring consistent somatotropin preparations.

All products listed are strictly for laboratory research use only and comply with EU research chemical regulations. Visit our homepage at euresearchpeptides.com to explore our complete catalogue of high purity peptides Germany and peptides for research France products. Buy research grade human growth hormone (HGH) Online EU

Sequence Information

Mature Human Growth Hormone Sequence (191 amino acids):

H₂N-FPTIPLSRLF DNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF-COOH

Sequence Notes:

  • The mature protein corresponds to residues 27-217 of the pre-protein

  • Contains two conserved disulfide bonds essential for tertiary structure

  • Four helical bundle topology characteristics of the somatotropin family


Purity Specifications (HPLC/MS Data)

All batches are accompanied by a Certificate of Analysis with the following validated parameters:

Quality Parameter Specification Method
Purity by HPLC ≥98% Reverse-phase HPLC
Purity by SDS-PAGE ≥98% Reducing and non-reducing
Mass Confirmation 22,125 ± 22 Da MALDI-TOF MS
Endotoxin <0.1 EU/µg LAL assay
Residual Host Cell Protein <100 ppm ELISA
Residual DNA <100 pg/mg qPCR
Biological Activity >1.0 × 10⁷ IU/mg Nb2-11 bioassay

Solubility Profile

Recombinant HGH demonstrates excellent solubility in aqueous buffers under appropriate conditions.

Recommended Reconstitution Buffer:

  • 100 mM Tris, pH 8.0, containing 1 mg/mL BSA and 0.05% Sodium Azide

  • Alternatively: Sterile PBS, pH 7.4 with 0.1% BSA

Solubility Characteristics:

Solvent System Solubility Recommended
Sterile water >1 mg/mL Yes (with BSA)
PBS pH 7.4 >1 mg/mL Yes
100 mM Tris pH 8.0 >2 mg/mL Yes (preferred)
Cell culture media >500 µg/mL Yes
0.1% BSA solution >5 mg/mL Yes (optimal)

Critical Solubility Notes:

  • Do NOT vortex after reconstitution; gentle inversion only

  • Allow reconstituted solution to sit for 30 minutes at 2-8°C for complete solubilization

  • Use borosilicate glass or polypropylene containers only; avoid polystyrene or polyethylene


Stability Data

Lyophilized Powder Stability

Storage Temperature Stability Period
-20°C 24+ months
2-8°C 12 months
Room temperature (short-term) 2 weeks

Reconstituted Solution Stability

Storage Temperature Stability Period
-20°C (aliquoted) 6 months
-80°C (aliquoted) 12 months
2-8°C 7-14 days
Room temperature 8-12 hours

Critical Stability Notes:

  • Avoid repeated freeze-thaw cycles

  • Prepare single-use aliquots immediately after reconstitution

  • Do NOT re-lyophilize reconstituted material


Recommended Storage Conditions

Lyophilized Product:

  • Store at -20°C in original container

  • Allow vial to reach room temperature before opening to prevent condensation

  • Protect from light and moisture

  • Desiccated environment recommended

Reconstituted Product:

  • Aliquot into working volumes immediately

  • Store aliquots at -20°C or -80°C

  • Label with concentration, date, and freeze-thaw count

  • Never refreeze thawed aliquots

Shipping Conditions:

  • Shipped at ambient temperature (lyophilized)

  • Upon receipt, transfer to -20°C for long-term storage


Known Research Applications

1. Cell Proliferation and Receptor Activation Studies

Recombinant HGH is validated for use in Nb2-11 lymphoma cell proliferation assays, a benchmark for growth hormone receptor activation. Research applications include:

  • Growth hormone receptor binding kinetics

  • JAK2/STAT5 signaling pathway investigation

  • Cell cycle progression analysis

  • IGF-1 secretion studies

2. Growth Plate and Chondrocyte Biology

For researchers studying skeletal growth and development:

  • Chondrocyte proliferation and differentiation assays

  • Alkaline phosphatase activity measurement

  • COL10A1, RUNX2, and OCN expression analysis

  • Matrix mineralization studies

3. Metabolic Research

HGH plays a central role in metabolic regulation:

  • Lipolysis and fatty acid oxidation studies

  • Glucose metabolism and insulin sensitivity research

  • Protein synthesis and nitrogen retention assays

  • Body composition and adipose tissue studies

4. Endocrine and Pituitary Research

  • Somatotropic axis investigation

  • Growth hormone deficiency modeling

  • Pituitary cell hormone secretion studies

  • IGF-1 feedback loop analysis

5. Cardiovascular Research

Recent studies have investigated HGH effects on cardiovascular biomarkers:

  • Endothelin-1 (ET-1) regulation

  • Asymmetric dimethylarginine (ADMA) studies

  • Oxidative stress parameter analysis

  • Total antioxidant capacity (TAC) assessment

6. Ocular Research

Bibliometric analyses have identified HGH research applications in ophthalmology:

  • Refractive status studies

  • Corneal curvature analysis

  • Intraocular pressure investigations

  • Myopia progression research

Citations and References

  • Labbé A, et al. Comparative Study of the Binding of Prolactin and Growth Hormone by Rabbit and Human Lung Cell Membrane Fractions. Biol Neonate. 1992; 61:179-187

  • Liu & Zhao. Recombinant GH in Idiopathic Short Stature Research. 2025

  • Kościuszko M, et al. Early Cardiovascular and Metabolic Benefits of rhGH Therapy. Int J Mol Sci. 2025; 26(12):5434

  • Ouyang R, et al. Global trends in recombinant human growth hormone for the treatment of idiopathic short stature. Front Med. 2025; 12:1577396


Proper Handling Protocols

Required Safety Equipment

  • Powder-free nitrile gloves

  • Safety goggles

  • Lab coat

  • Biosafety cabinet (for reconstitution)

Handling Precautions

All research chemicals EU compliant products require:

  • Work in designated laboratory areas only

  • Avoid skin contact and inhalation of aerosolized powder

  • Decontaminate spills with appropriate disinfectant

  • Document all usage in laboratory records

Quality Control Before Use

  1. Inspect vial for any damage or compromised seal

  2. Centrifuge briefly to collect powder at bottom

  3. Allow vial to equilibrate to room temperature

  4. Confirm absence of clumping or discoloration


Reconstitution Guidelines

Standard Protocol for Cell Culture Applications

Materials Required:

  • Sterile PBS pH 7.4 or 100 mM Tris pH 8.0

  • Sterile 0.1% BSA solution

  • Sterile syringe and needle

  • Alcohol prep pads

Procedure:

  1. Preparation: Clean work surface and allow lyophilized HGH vial to reach room temperature (approximately 20 minutes)

  2. Carrier Protein Addition: Reconstitute with buffer containing 0.1% BSA to minimize adsorption losses and maximize protein stability

  3. Gentle Reconstitution: Add calculated volume of buffer slowly down the inner glass wall. Target concentration of 1 mg/mL for stock solutions

  4. Solubilization Period: Allow reconstituted solution to sit for 30 minutes at 2-8°C to ensure complete solubilization

  5. Aliquoting: Divide into single-use aliquots. Do NOT freeze-thaw repeatedly

  6. Storage: Store aliquots at -20°C or -80°C immediately

Concentration Calculator

Desired Concentration Peptide Mass (1 mg vial) Diluent Volume
1 mg/mL 1 mg 1.0 mL
2 mg/mL 1 mg 0.5 mL
0.5 mg/mL 1 mg 2.0 mL
0.2 mg/mL 1 mg 5.0 mL

Safety Considerations

Hazard Identification

  • For laboratory research use only

  • Not for human or veterinary consumption

  • May cause skin and eye irritation upon contact

First Aid Measures

  • Skin contact: Wash immediately with soap and water

  • Eye contact: Rinse thoroughly with water for 15 minutes

  • Inhalation: Move to fresh air, seek medical attention if respiratory irritation occurs

  • Ingestion: Do NOT induce vomiting; seek immediate medical attention

Handling and Storage

  • Store locked and secured from unauthorized access

  • Maintain accurate inventory records

  • Dispose of unused material as chemical waste per local regulations


Why Choose Euresearchpeptides.com

As a premium EU-based online retailer specializing in laboratory peptides Netherlands and peptide supplier Spain markets, we provide:

  • EU Warehousing – Fast shipping across Germany, France, Netherlands, Spain, Italy, Belgium, and all EU member states

  • Documented Purity – Every batch includes Certificate of Analysis with HPLC and MS data

  • EU Regulatory Compliance – Full adherence to research chemicals EU compliant standards

  • Technical Support – Expert guidance for reconstitution and experimental protocols

  • Discreet Professional Packaging – Laboratory-grade packaging with cold chain options

For BPC-157 Europe, GLP-1 research peptides EU, or peptide synthesis Europe requirements, trust Euresearchpeptides.com as your dedicated research partner.


 FAQ Section

Q1: Where can I buy research grade human growth hormone for laboratory studies in Europe?

You can purchase high purity recombinant human growth hormone directly from euresearchpeptides.com, a trusted buy peptides EU supplier with warehouse operations across Europe. We offer documented purity (>98% by HPLC) and fast shipping to all EU countries. Shop now

Q2: What is the purity of your research HGH product?

Our recombinant human growth hormone is tested at >98% purity by both SDS-PAGE and HPLC, with endotoxin levels <0.1 EU/µg. Each shipment includes a Certificate of Analysis with batch-specific data for high purity peptides Germany research standards. View specifications

Q3: How should I reconstitute lyophilized HGH for cell culture studies?

Reconstitute in sterile PBS pH 7.4 or 100 mM Tris pH 8.0 containing 0.1% BSA to prevent adsorption losses. Allow 30 minutes at 2-8°C for complete solubilization. For peptides for research France applications, follow our detailed reconstitution protocol above. Get protocol

Q4: What is the molecular weight of human growth hormone?

Human growth hormone (somatotropin) has a molecular weight of approximately 22 kDa (22,000 Daltons) and consists of 191 amino acids. This is the mature, biologically active form used in laboratory peptides Netherlands research. Technical data

Q5: How should I store reconstituted HGH?

Reconstituted HGH should be aliquoted immediately and stored at -20°C. Avoid repeated freeze-thaw cycles. Under these conditions, stability is maintained for 6 months. For peptide supplier Spain customers, we provide detailed storage recommendations with each shipment. Storage guide

Q6: What biological activity does your HGH product have?

Our recombinant HGH is validated in the Nb2-11 lymphoma cell proliferation assay with ED50 <0.1 ng/mL, representing >1.0×10⁷ IU/mg specific activity – suitable for research SARMs and endocrine research applications. View bioassay data

Q7: Do you ship to my country in Europe?

We ship to all EU member countries including Germany, France, Netherlands, Spain, Italy, Belgium, Austria, Switzerland, Sweden, Denmark, and more as a leading research chemicals EU compliant distributor of research peptides and proteins. Check shipping

Q8: What is the difference between pituitary-derived and recombinant HGH?

Our HGH is recombinant, produced in E. coli expression systems, ensuring batch-to-batch consistency and eliminating variability associated with BPC-157 Europe or pituitary-derived products. Recombinant production also ensures no animal-origin contaminants. Learn more

Q9: Can this HGH be used for in vivo research studies?

Our HGH is intended for in vitro laboratory research only. For GLP-1 research peptides EU or in vivo applications, please contact our technical support team to discuss appropriate product specifications and compliance requirements. Contact us

Q10: What is your quality guarantee for research products?

All research products from euresearchpeptides.com are covered by our quality guarantee. If product does not meet specified purity or activity standards, contact us within 14 days of receipt for peptide synthesis Europe accessory concerns. Return policy

Reviews

There are no reviews yet.

Be the first to review “HGH”

Your email address will not be published. Required fields are marked *