SLU-PP-332

Price range: €141.00 through €278.00

Product Overview
Attribute Specification
Brand euresearchpeptides.com
Product Name SLU-PP-332
CAS Number 303760-60-3
Molecular Formula C18H14N2O2
Molecular Weight 290.32 g/mol
Purity ≥99% (HPLC-MS verified)
IUPAC Name 4-hydroxy-N’-(2-naphthylmethylene)benzohydrazide
Appearance White to off-white solid powder
Solubility (DMSO) 58–125 mg/mL (ultrasonic assistance)
Solubility (Ethanol) 2 mg/mL
Solubility (Water) Insoluble
Storage (Powder) -20°C, 3 years
Storage (Solution) -80°C, 6 months; -20°C, 1 month
Stability Notes Avoid repeated freeze-thaw; protect from light
Packaging Sealed vial with desiccant; tamper-evident seal
Country of Origin EU (manufactured in Germany)
Shipping Restrictions Research use only; not for human consumption
Safety Classification R28 (very toxic if swallowed), R38 (irritating to skin), R41 (risk of serious eye damage), R62/R63 (reproductive hazards)
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Description

Buy SLU-PP-332 Peptides online

Welcome to euresearchpeptides.com — your trusted EU-based partner for high-purity research peptides, SARMs, and specialty biochemicals. We supply SLU-PP-332 (CAS: 303760-60-3), a first-in-class pan-estrogen-related receptor (ERR) agonist, to research institutions, pharmaceutical laboratories, and qualified buyers across Europe and worldwide. buy SLU-PP-332 research peptide

What Is SLU-PP-332?

SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptors ERRα, ERRβ, and ERRγ . This compound has gained significant attention in metabolic research for its ability to mimic certain physiological effects of aerobic exercise at the molecular level. buy SLU-PP-332 research peptide

Developed by researchers at Saint Louis University, SLU-PP-332 activates a transcriptional program associated with increased energy expenditure, fatty acid oxidation, and mitochondrial biogenesis . For laboratory use only, this compound is NOT for human consumption.

Key Research Applications

Application Area Description
Metabolic Syndrome Research Studies on obesity, insulin sensitivity, and glucose tolerance
Mitochondrial Biology Investigation of oxidative metabolism and mitochondrial function
Skeletal Muscle Physiology Research on muscle fiber type switching and endurance capacity
Aging & Metabolic Health Models of age-related metabolic decline

How SLU-PP-332 Works: Mechanism of Action

SLU-PP-332 functions as a pan-ERR agonist, binding to and activating all three ERR isoforms with the following potency profile :

  • ERRα: EC50 = 98 nM (highest affinity)

  • ERRβ: EC50 = 230 nM

  • ERRγ: EC50 = 430 nM

The estrogen-related receptors (ERRα, ERRβ, ERRγ) are constitutively active nuclear receptors highly expressed in energy-demanding tissues including skeletal muscle, heart, liver, and brown adipose tissue . ERR target genes encode proteins involved in:

  • Fatty acid oxidation

  • Mitochondrial biogenesis

  • Krebs cycle enzymes

  • Oxidative phosphorylation

By activating these receptors, SLU-PP-332 induces a transcriptional program that mimics key adaptations to aerobic exercise, including increased resting energy expenditure and enhanced fatty acid utilization .

Performance Benefits in Research Models

Published studies in Journal of Pharmacology and Experimental Therapeutics demonstrate that SLU-PP-332 administration in mouse models produces :

Parameter Observed Effect
Energy Expenditure Significant increase in resting metabolic rate
Fat Mass Accumulation Decreased adiposity in diet-induced obese mice
Insulin Sensitivity Improved glucose tolerance
Fatty Acid Oxidation Enhanced whole-body lipid utilization

These effects were achieved at a dose of 50 mg/kg administered intraperitoneally twice daily over 28 days .

Safety Considerations & Handling Protocols

SLU-PP-332 is a potent bioactive compound requiring strict laboratory handling procedures.

Hazard Identification :

  • Toxic. Contains a pharmaceutically active ingredient

  • Moderate to severe irritant to skin and eyes

  • Possible risk of impaired fertility (R62)

  • Possible risk of harm to unborn child (R63)

Required Personal Protective Equipment (PPE) :

  • Chemical-resistant rubber gloves

  • Chemical safety goggles

  • NIOSH/MSHA-approved respirator

  • Laboratory coat

First Aid Measures :

  • Inhalation: Remove to fresh air; administer oxygen if breathing difficulty occurs

  • Skin contact: Flush with copious water; remove contaminated clothing

  • Eye contact: Flush with water for 15+ minutes while holding eyelids open; seek medical attention

  • Ingestion: Rinse mouth with water; seek immediate medical attention

Storage Requirements:

  • Store powder at -20°C (3 years stability)

  • Stock solutions in DMSO: -80°C (6 months) or -20°C (1 month)

  • Protect from light and moisture

  • Avoid repeated freeze-thaw cycles

Reconstitution Guidelines

SLU-PP-332 demonstrates the following solubility profile :

Solvent Solubility
DMSO 58-125 mg/mL (199-430 mM) – ultrasonic assistance recommended
Ethanol 2 mg/mL (limited)
Water Insoluble
In vivo formulations 5% DMSO + 40% PEG300 + 5% Tween80 + 50% ddH2O; or 5% DMSO + 95% corn oil

Preparation Protocol:

  1. Prepare DMSO stock solution at desired concentration

  2. For in vivo use, dilute stock into vehicle following the sequential addition method

  3. Ensure clear solution at each step before adding next solvent

  4. Use immediately for optimal results

Why Researchers Choose euresearchpeptides.com

As a premier peptides supplier Europe, we differentiate ourselves through:

European-Based Operations
Our EU warehouse network ensures fast, compliant shipping to Germany, France, Netherlands, Spain, Italy, and all European destinations.

Certified Quality
Every batch of SLU-PP-332 undergoes rigorous HPLC-MS and NMR analysis with purity ≥99%. Certificates of Analysis (COA) accompany every shipment.

Regulatory Compliance
We adhere to all applicable EU regulations including REACH, CLP, and national research chemical laws.

Technical Support
Our in-house scientific team provides formulation guidance, protocol assistance, and troubleshooting.

Supply Chain Reliability
No backorders. No substitution quality. Real-time inventory visibility.

Who Should Buy SLU-PP-332?

This product is intended for:

User Type Suitability
Academic Research Labs Metabolic studies, exercise physiology, obesity research
Pharmaceutical R&D Drug discovery, target validation, preclinical development
CROs & CMOs Contract research requiring reliable biochemicals
Graduate & Postdoctoral Researchers Thesis work in metabolism, mitochondria, or endocrinology

This product is NOT for:

  • Human or animal therapeutic use

  • Nutritional or dietary supplementation

  • Personal consumption or “biohacking”

  • Unsupervised laboratory use

Ordering Information

Catalog Number: EU-SLU-332
CAS Number: 303760-60-3
Molecular Formula: C18H14N2O2
Molecular Weight: 290.32 g/mol
Purity: ≥99% (HPLC)
Available Sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, bulk quantities upon request
Shipping: Ambient temperature within EU; ice packs for extended transit
Lead Time: In-stock items ship within 24 hours

👉 Browse our complete research peptide catalog at euresearchpeptides.com.

Frequently Asked Questions (FAQ) – High Commercial Intent

Q1: Where can I buy SLU-PP-332 for research in Europe?
You can purchase high-purity SLU-PP-332 from euresearchpeptides.com, a trusted EU-based supplier of research peptides. We ship to Germany, France, Netherlands, Spain, Italy, UK, Switzerland, and all European countries. Order online for fast, compliant delivery.

Q2: What is the purity of your SLU-PP-332?
Our SLU-PP-332 is verified at ≥99% purity by HPLC-MS and NMR analysis. Each shipment includes a Certificate of Analysis (COA) with batch-specific purity data, residual solvent analysis, and heavy metals testing.

Q3: How should I store SLU-PP-332 powder?
Store SLU-PP-332 powder at -20°C in a sealed, light-protected container. Under these conditions, stability is maintained for up to 3 years . Avoid repeated freeze-thaw cycles. Stock solutions in DMSO should be aliquoted and stored at -80°C for up to 6 months.

Q4: What is the solubility of SLU-PP-332?
SLU-PP-332 is soluble in DMSO at 58-125 mg/mL with ultrasonic assistance. It has limited solubility in ethanol (2 mg/mL) and is insoluble in water . For in vivo studies, use 5% DMSO + 40% PEG300 + 5% Tween80 + 50% ddH2O or 5% DMSO + 95% corn oil.

Q5: Is SLU-PP-332 legal to buy in the EU?
SLU-PP-332 is a research chemical not scheduled under EU or national drug laws. It may be purchased by qualified research institutions, laboratories, and individuals for legitimate scientific research purposes. Buyers are responsible for compliance with local regulations. euresearchpeptides.com ships in full compliance with EU chemical regulations.

Q6: What research has been published on SLU-PP-332?
SLU-PP-332 has been featured in peer-reviewed publications including the Journal of Pharmacology and Experimental Therapeutics (2024) and ACS Chemical Biology (2023). Studies demonstrate its efficacy as an ERR agonist that increases energy expenditure, reduces fat mass, and improves insulin sensitivity in mouse models of obesity and metabolic syndrome .

Q7: How quickly do you ship SLU-PP-332 orders?
In-stock SLU-PP-332 orders placed before 12:00 CET ship same business day. Delivery within EU typically takes 2-5 business days. Express shipping options are available at checkout. All shipments include proper documentation for customs clearance.

Q8: Do you offer bulk or wholesale pricing for SLU-PP-332?
Yes. For orders of 100 mg or larger, please contact our sales team for custom pricing. We supply research institutions, pharmaceutical companies, and CROs with bulk quantities tailored to your research needs.

Q9: What safety precautions are required when handling SLU-PP-332?
SLU-PP-332 is toxic and an irritant. Always handle in a fume hood wearing chemical-resistant gloves, safety goggles, and a lab coat. In case of skin or eye contact, flush immediately with copious water and seek medical attention .

Q10: Can I return SLU-PP-332 if I am unsatisfied?
Due to the nature of research chemicals, we cannot accept returns for reasons other than product quality defects. If you receive a damaged or non-conforming product, contact us within 14 days with batch information for replacement or refund.

Additional information

500mcg

1mg, 250mcg, 500mcg

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