Description

Buy Epithalon 10mg Peptide | High Purity Research Peptide Europe

Welcome to euresearchpeptides.com — your trusted source for premium, laboratory-grade research peptides in Europe. Our Epithalon 10mg peptide (also known as Epitalon or Epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) widely studied for its effects on telomerase activity, cellular aging pathways, and circadian rhythm regulation in research settings. buy epithalon 10mg peptide Europe

What Is Epithalon Peptide?

Epithalon is a synthetic tetrapeptide consisting of four amino acids: alanine (Ala), glutamic acid (Glu), aspartic acid (Asp), and glycine (Gly) with the sequence AEDG. It was originally developed from research on Epithalamin, a naturally occurring polypeptide complex extracted from bovine pineal gland tissue and was first confirmed as naturally present in human pineal tissue in 2017. buy epithalon 10mg peptide Europe

This peptide is strictly intended for laboratory research use only and is not for human consumption. Our Epithalon 10mg is manufactured using solid-phase peptide synthesis (SPPS) and purified via high-performance liquid chromatography (HPLC) to achieve purity exceeding 99%. buy epithalon 10mg peptide Europe

How Epithalon Works: Mechanism of Action in Research

In preclinical research models, Epithalon exerts its biological effects through several well-characterized mechanisms:

Telomerase Activation and Telomere Maintenance: Epithalon has been shown to induce telomerase enzyme activity, resulting in the extension of telomere length in normal healthy mammalian cells through the upregulation of hTERT mRNA expression. Telomeres are the protective caps at the ends of chromosomes that shorten with each cell division, and telomere length is considered a key biomarker of cellular aging.

Pineal Gland Regulation and Circadian Biology: Epithalon influences pineal gland function and has been correlated with enhanced melatonin synthesis in research models. Studies in older primates suggest that Epithalon may help restore melatonin rhythms to levels closer to those seen in younger animals.

Antioxidant and Neuroprotective Effects: Research has demonstrated Epithalon’s antioxidant activity with the ability to reduce free radicals, as well as neuroprotective effects in retinal tissue studies.

Immune Modulation: Studies indicate immunomodulatory effects, including altered mRNA levels of interleukin-2 and enhanced immune markers.

Research Applications

Epithalon peptide is utilized across multiple research domains:

Performance Specifications for Research

Solubility Profile

Epithalon demonstrates excellent solubility in aqueous solutions:

Reconstitution Guideline for 10mg Vial:

• Add 1 mL bacteriostatic water for 10 mg/mL concentration

• Add 2 mL for 5 mg/mL concentration

• Gently swirl until fully dissolved — do not shake

• Use sterile technique and avoid foaming

Stability and Storage Recommendations

Handling Protocols

For research use only. Proper handling ensures experimental integrity:

1. Allow vials to reach room temperature before opening to minimize condensation

2. Reconstitute by injecting diluent slowly down the vial wall

3. Gently swirl or roll until fully dissolved — never shake vigorously

4. Label with date, concentration, and lot number

5. Store reconstituted peptide at 2-8°C and use within 30 days

6. Never use peptide solutions that appear cloudy or contain particulate matter

Quality Standards at EU Research Peptides

Our Epithalon 10mg peptide is manufactured under strict quality control protocols:

• Synthesis: Solid-phase peptide synthesis (SPPS) with Fmoc chemistry

• Purification: HPLC purification to >99% purity

• Verification: Mass spectrometry (MS) confirmation of molecular weight

• Quality Control: Each batch includes Certificate of Analysis (COA) with HPLC chromatogram and MS spectrum

• Facility: ISO-classified cleanroom manufacturing

Why Researchers Choose EU Research Peptides

European-Based Operations: We are strategically located in the EU, ensuring fast, reliable shipping across Europe without customs delays.

Premium Quality: Every peptide batch undergoes rigorous third-party testing for purity, stability, and endotoxin levels.

Research Compliance: All products are labeled “For Research Use Only” and comply with EU chemical regulations including REACH and CLP.

Technical Support: Our team provides comprehensive documentation including COAs, MSDS, and reconstitution protocols.

Competitive Pricing: Bulk discounts available for research institutions and volume orders.

👉 Explore our complete catalog of research peptides at our official homepage.

Safety Considerations

Epithalon peptide is intended for laboratory research purposes only. It is not for human consumption, therapeutic use, or veterinary applications. Important safety notes from current literature:

• In theory, sustained telomerase activation may interact differently with cells in individuals with active malignancy; proper medical evaluation is essential before any research involving human subjects

• Long-term safety data in humans are limited

• Researchers should follow institutional biosafety guidelines

• Use appropriate personal protective equipment (PPE)

• Dispose of materials according to local regulations

Frequently Asked Questions (FAQ)

What is Epithalon peptide?

Epithalon (also written as Epitalon or Epithalone) is a synthetic tetrapeptide composed of four amino acids: alanine, glutamic acid, aspartic acid, and glycine (sequence AEDG). It was developed from research on Epithalamin, a bovine pineal gland extract, and was first detected in human pineal tissue in 2017.

What is the molecular formula and weight of Epithalon?

The molecular formula is C14H22N4O9 with a molecular weight of 390.35 g/mol. The CAS number is 307297-39-8.

What purity level does EU Research Peptides offer for Epithalon?

Our Epithalon 10mg peptide is tested at >99% purity by HPLC with mass spectrometry confirmation. Each batch includes a Certificate of Analysis (COA) with detailed purity data.

How does Epithalon work in research models?

Epithalon has been shown to induce telomerase enzyme activity, resulting in the extension of telomere length in normal healthy mammalian cells through the upregulation of hTERT mRNA expression. It also influences pineal gland function and melatonin regulation.

Is Epithalon soluble in water?

Yes, Epithalon is highly soluble in water with solubility of 78 mg/mL (199.82 mM). It is also soluble in DMSO but insoluble in ethanol.

What is the recommended storage for Epithalon?

Lyophilized Epithalon should be stored at -20°C or below, kept desiccated, and protected from light. In lyophilized form, it is stable for 36 months. After reconstitution, refrigerate at 2-8°C and use within 30 days.

What are the primary research applications for Epithalon?

Epithalon is studied in longevity and aging research (telomere maintenance), circadian rhythm studies (melatonin regulation), immunology research (immune modulation), neuroendocrinology, and oxidative stress research.

What is the recommended reconstitution protocol for 10mg Epithalon?

For a 10mg vial, add 1 mL of bacteriostatic water to achieve 10 mg/mL concentration. For a less concentrated solution (5 mg/mL), add 2 mL of diluent. Gently swirl until fully dissolved — do not shake.

Can I purchase Epithalon in larger quantities?

Yes, EU Research Peptides offers volume discounts for bulk orders. Contact our customer service team for customized quotes on larger quantities.

What documentation is provided with each order?

Each order includes a Certificate of Analysis (COA), material safety data sheet (MSDS), and reconstitution protocol.

Is Epithalon FDA approved?

No, Epithalon is not FDA approved for any therapeutic indication. It is classified as experimental in most jurisdictions and is strictly for laboratory research use only.

What are the key scientific limitations of Epithalon research?

Key findings in lifespan extension and tumor inhibition have not been widely replicated by independent international research groups. Most published findings come from animal models or in vitro studies, not controlled human trials.