Description

Buy Density Labs LGD-4033 Ligandrol | High Purity Research SARM Europe

Welcome to euresearchpeptides.com — your premier EU-based supplier of research peptides and SARMs for laboratory use. We are proud to offer Density Labs LGD-4033 Ligandrol, a high-purity selective androgen receptor modulator (SARM) intended exclusively for scientific research and forensic applications. buy lgd-4033 ligandrol europe

What Is LGD-4033 Ligandrol?

LGD-4033, also known as Ligandrol, Anabolicum, or VK5211, is a nonsteroidal selective androgen receptor modulator developed by Ligand Pharmaceuticals and subsequently researched by Viking Therapeutics. Unlike traditional anabolic agents, LGD-4033 demonstrates selective binding affinity to androgen receptors in muscle and bone tissues while showing minimal interaction with prostate, sebaceous glands, and other off-target tissues. buy lgd-4033 ligandrol europe

CAS Number: 1165910-22-4
Molecular Formula: C14H12F6N2O
Molecular Weight: 338.25 g/mol

This compound is classified as an investigational new drug and has not received regulatory approval for human or veterinary use. It is supplied exclusively as a reference material for laboratory research, including HPLC method development, in vitro metabolism studies, and doping control research. buy lgd-4033 ligandrol europe

How LGD-4033 Works: Androgen Receptor Binding

As a SARM, LGD-4033 functions by binding selectively to androgen receptors (AR) with a reported Ki value of approximately 1 nM . This binding affinity triggers tissue-selective activation of androgenic signaling pathways. Key mechanisms include:

• Selective Tissue Targeting: Unlike testosterone, LGD-4033 preferentially targets anabolic pathways in skeletal muscle and bone while demonstrating reduced activity in prostate tissue

• Non-Aromatizing Structure: The molecule does not convert to estrogen or dihydrotestosterone (DHT), distinguishing it from traditional steroidal compounds

• Oral Bioavailability: The compound maintains stability for oral administration in research models

• Half-Life Profile: Research indicates a half-life of approximately 24-36 hours, supporting once-daily dosing in controlled study protocols

Research Applications & Performance Characteristics

LGD-4033 has been extensively studied in the scientific literature for various research applications:

Purity Specifications & Quality Standards

Density Labs LGD-4033 meets rigorous quality specifications:

• Purity: ≥98% (HPLC verified)

• Form: Crystalline solid / Liquid solution (10mg/ml concentration available)

• Solubility: DMF: 25 mg/ml, DMSO: 10 mg/ml, Ethanol: 25 mg/ml

• Spectroscopic Data: Validated via NMR and LC/ESI-HRMS

• Batch Specific Documentation: Certificate of Analysis (COA) available for each production batch

Metabolic Profiling & Detection Research

Comprehensive research has identified multiple LGD-4033 metabolites relevant to doping control and pharmacokinetic studies:

Phase I Metabolites (Hydroxylated Species):

• Monohydroxylated metabolites (M1, M2, M2c)

• Bishydroxylated metabolites (M5a, M5b, M3)

• The main bishydroxylated long-term metabolite has been structurally revised to 4-arylamino-5-hydroxyhexanoic acid

Phase II Metabolites:

• Glucuronic acid conjugates have been identified in camel liver studies

Emerging Research:

• A recently characterized pyrrole derivative metabolite (M8) demonstrates antagonistic activity on the androgen receptor and may serve as a marker for recent substance intake

Safety Considerations & Handling Protocols

LGD-4033 is a potent research compound requiring appropriate laboratory safety measures:

Proper Handling:

• Use appropriate personal protective equipment (PPE): gloves, lab coat, safety goggles

• Work in a well-ventilated area or fume hood

• Avoid skin contact, inhalation, and ingestion

• Wash thoroughly after handling

Storage Recommendations:

• Store at -20°C for long-term preservation

• Protect from light and moisture

• Keep container tightly sealed

• Stable for 12-18 months under recommended conditions

Regulatory Status:

• LGD-4033 is listed on the WADA Prohibited List under the category “Other Anabolic Agents”

• Not approved for human or veterinary use

• Supplied exclusively for research and forensic applications

Who Is This Product Best Suited For?

• Research Laboratories: Analytical method development and validation

• Doping Control Facilities: Reference material for anti-doping testing protocols

• Pharmaceutical Researchers: In vitro metabolism studies and receptor binding assays

• Forensic Scientists: Identification and quantification of SARMs in biological samples

• Educational Institutions: Teaching laboratories for analytical chemistry

Why Researchers Trust euresearchpeptides.com

As a premium EU-based research chemical supplier, we serve customers searching for buy peptides EU, high purity peptides Germany, peptides for research France, laboratory peptides Netherlands, and peptide supplier Spain.

Our Commitments:

• Verified Purity: Every batch is HPLC-tested with ≥98% purity minimum

• European Distribution: Faster shipping, no customs delays within EU

• Comprehensive Documentation: COA, MSDS, and technical data sheets included

• Discreet Packaging: Professional, tamper-evident packaging for laboratory integrity

• Customer Support: Technical assistance from knowledgeable staff

👉 Explore our complete research chemical catalog at our official homepage.

 

Frequently Asked Questions About LGD-4033 Ligandrol

Q1: What is LGD-4033 Ligandrol used for in research?
LGD-4033 is a selective androgen receptor modulator (SARM) used in laboratory research applications including androgen receptor binding studies, metabolic profiling, doping control method development, and in vitro investigations of anabolic pathways .

Q2: What is the purity of Density Labs LGD-4033?
Density Labs LGD-4033 is verified at ≥98% purity by HPLC analysis, consistent with analytical reference standards used in forensic and pharmaceutical research .

Q3: How should LGD-4033 be stored in the laboratory?
For optimal stability, store LGD-4033 at -20°C, protected from light and moisture. The compound remains stable for 12-18 months under these conditions .

Q4: Is LGD-4033 soluble in common laboratory solvents?
LGD-4033 demonstrates solubility in DMF (25 mg/ml), DMSO (10 mg/ml), and ethanol (25 mg/ml). For aqueous solutions, ethanol:PBS (pH 7.2) at 1:5 ratio yields 0.16 mg/ml solubility .

Q5: What metabolites of LGD-4033 have been identified in research?
Research has identified multiple Phase I metabolites including mono- and bishydroxylated species, as well as Phase II glucuronic acid conjugates. The main bishydroxylated long-term metabolite has been structurally characterized .

Q6: Is LGD-4033 on the WADA Prohibited List?
Yes, LGD-4033 is classified as a prohibited substance by the World Anti-Doping Agency under the category “Other Anabolic Agents” and is monitored in anti-doping testing protocols .

Q7: Can I buy LGD-4033 for research in Europe?
Yes, euresearchpeptides.com supplies high-purity LGD-4033 to qualified researchers and institutions across the European Union for laboratory use only .

Q8: What documentation is provided with each order?
Each order includes a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and batch-specific documentation verifying purity and chemical identity.

Q9: What safety precautions should be taken when handling LGD-4033?
Researchers should use appropriate PPE including gloves, lab coat, and safety goggles. Work should be conducted in a fume hood with proper ventilation. Avoid skin contact, inhalation, and ingestion .

Q10: Is LGD-4033 approved for human or veterinary use?
No. LGD-4033 is an investigational compound that has not received regulatory approval for human or veterinary use. It is supplied exclusively as a reference material for scientific research .